DONELLO, JOHN E.,YANG, RONG,LEBLOND, BERTRAND,BEAUSOLEIL, ERIC,CASAGRANDE, ANNE-SOPHIE,DESIRE, LAURENT J.R.,PANDO, MATTHEW P.,CHAUVIGNAC, CEDRIC,TAVERNE, THIERRY
申请号:
CA2827724
公开号:
CA2827724A1
申请日:
2012.02.17
申请国别(地区):
CA
年份:
2012
代理人:
摘要:
The invention relates to compounds of the formula wherein R', R1 through R7 and Ar are as defined herein. These compounds are useful as inhibitors of phosphodiesterase 10 (PDE10A) which are useful in treating central nervous system diseases such as psychosis and also in treating, for example, obesity, type II diabetes, metabolic syndrome, glucose intolerance, pain and ophthalmic diseases.