Laurent Désiré;Eric Beausoleil;Matthew P. Pando;John E. Donello;Rong Yang;Cédric Chauvignac;Anne-Sophie Casagrande;Bertrand Leblond;Thierry Taverne
发明人:
Bertrand Leblond,Cédric Chauvignac,Thierry Taverne,Eric Beausoleil,Anne-Sophie Casagrande,Laurent Désiré,Matthew P. Pando,John E. Donello,Rong Yang
申请号:
US13399351
公开号:
US20120214837A1
申请日:
2012.02.17
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The invention relates to compounds of the formulawherein R′, R1, through R7 and Ar are as defined herein. These compounds are useful as inhibitors of phosphodiesterase 10 (PDE10A) which are useful in treating central nervous system diseases such as psychosis and also in treating, for example, obesity, type II diabetes, metabolic syndrome, glucose intolerance, pain and ophthalmic diseases.