The present invention relates to benzofuran derivatives, the preparation method and medical use thereof. Specifically, the present invention relates to a novel benzofuran derivative represented by formula (I), the preparation methods thereof, the pharmaceutical composition containing the same, the use of the same as a therapeutic agent especially as proton pump inhibitors and potassium-compctitivc acid blockers (P-CABs), wherein the respective substituents of formula (I) are as those defined in the specification.本發明涉及苯並呋喃類衍生物、其製備方法及其在醫藥上的應用。具體而言,本發明涉及一種通式(I)所示的新的苯並呋喃類衍生物、其製備方法及含有該衍生物的醫藥組成物以及其作為治療劑,特別是作為胃酸分泌抑制劑和鉀離子競爭性酸阻滯劑(P-CABs)的用途,其中通式(I)的各取代基與說明書中的定義相同。