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משטר מינון למעכב סלקטיבי של איזופורם אלפא של פוספטידילינוסיטול 3–קינאז
专利权人:
NOVARTIS AG
发明人:
申请号:
IL24570916
公开号:
IL245709D0
申请日:
2016.05.18
申请国别(地区):
IL
年份:
2016
代理人:
摘要:
The present invention relates to methods of treating or preventing a proliferative disease in a patient in need thereof by orally administering a therapeutically effective amount of an alpha-isoform selective phosphatidylinositol 3-kinase inhibitor compound of formula (I) or a pharmaceutically acceptable salt thereof for at least two five-consecutive day cycle, wherein said compound is not administered to the patient for a period of about two days to about three days between said five-consecutive day cycles; the use of said compound of formula (I) or a pharmaceutically acceptable salt thereof for the manufacture of a medicament for treating or preventing a proliferative disease administered in accordance with said dosage regimen; therapeutic regimen comprising administration of said compound of formula (I) or a pharmaceutically acceptable salt thereof in accordance with said dosage regimen; and related pharmaceutical compositions and packages thereof.
来源网站:
中国工程科技知识中心
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