This disclosure relates to pharmaceutical compositions for preventing, treating, reducing the duration, or reducing the severity of symptoms of the common cold. The pharmaceutical composition can comprise a probiotic formulation of non-pathogenic bacteria, vitamin C and vitamin D along with a pharmaceutically acceptable excipient or filler. A method of for preventing, treating, reducing the duration, or reducing the severity of symptoms of the common cold is also disclosed in which a patient in need of a treatment for preventing, treating, reducing the duration, or reducing the severity of symptoms of the common cold is identified. The pharmaceutical composition can then be administered orally to the patient.