Provided are a spider venom (SV) 82 polypeptide having an amino acid sequence of SEQ ID NO: 2, a SV82 polypeptide-encoding gene having a nucleotide sequence of SEQ ID NO: 1 which is optimized for E. coli codon, a recombinant vector comprising the SV82 polypeptide-encoding gene, a E. coli transformed with the recombinant vector, a method of producing SV82 polypeptide by transforming a host cell with the recombinant vector, and a cosmetic composition for reducing skin wrinkles and maintaining skin elasticity comprising SV82 polypeptide as an active ingredient.
