Novel piperazine and piperidine derivatives, their synthesis and use thereof in inhibiting VDAC oligomerization, apoptosis and mitochondria dysfunction
The National Institute for Biotechnology in the Negev Ltd.
发明人:
Shoshan-Barmatz, Varda,Lev Gruzman, Arie
申请号：
AU2016325108
公开号：
AU2016325108A1
申请日:
2016.09.13
申请国别(地区):
AU
年份:
2018
代理人:
摘要：
Provided herein piperazine and piperidine derivatives, their synthesis and use thereof in inhibiting VDAC oligomerization, apoptosis and mitochondria dysfunction. Also provided methods of treatment of diseases associated with said processes, e.g. Alzheimer's disease.
