PROCESS FOR THE PREPARATION OF 2 {4 [2 ({[2 (4 CHLOROPHENYL) 1 3 THIAZOL 4 YL]METHYL}SULFANYL) 3 5 DICYANO 6 (PYRROLIDIN 1 YL)PYRIDIN 4 YL]PHENOXY}ETHYL L ALANYL L ALANINATE MONOHYDROCHLORIDE

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专利权人:

发明人:

MAIS FRANZ JOSEF,HEILMANN WERNER,OLENIK BRITTA,KEIL BIRGIT,BECKER GUIDO,MEIBOM DANIEL,KUHLMANN THOMAS

申请号：

IN201717035930

公开号：

IN201717035930A

申请日:

2017.10.10

申请国别(地区):

IN

年份:

2017

代理人:

摘要：

The present invention relates to a novel and improved process for the preparation of the compound 2 {4 [2 ({[2 (4 chlorophenyl) 1 3 thiazol 4 yl]methyl}sulfanyl) 3 5 dicyano 6 (pyrrolidin 1 yl) pyridin 4 yl] phenoxy} ethyl L alanyl L alaninate monohydrochloride of formula (I) new precursors for their preparation as well as to the production and use of the crystalline modification I of 2 {4 [2 ({[2 (4 chlorophenyl) 1 3 thiazol 4 yl]methyl}sulfanyl) 3 5 dicyano 6 (pyrrolidin 1 yl)pyridin 4 yl]phenoxy}ethyl L alanyl L alaninate monohydrochloride of formula (I).

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