METHOD FOR EXPRESSING PROTEIN GENE IN RESPONSE TO EXPRESSION OF MIRNA

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专利权人:

KYOTO UNIVERSITY

发明人:

SAITO, Hirohide,FUJITA, Yoshihiko

申请号：

WO2017JP23513

公开号：

WO2018003779(A1)

申请日:

2017.06.27

申请国别(地区):

世界知识产权组织国际局

年份:

2018

代理人:

摘要：

Provided are a mRNA that forcibly expresses a protein gene in response to a miRNA, and a method for forcibly expressing the same. This artificial mRNA comprises: a sequence that encodes a protein gene; a miRNA target sequence connected to the 3' side of a PolyA sequence; and a translation repression sequence connected to the 3' side of the miRNA target sequence. Also disclosed is a method for expressing a protein gene in response to the expression of a miRNA, the method comprising a step for introducing said artificial mRNA into a cell.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/