PROCEDURE FOR CREATING SINGLE-VL DOMAIN ANTIBODIES OF TRANSGENE ANIMALS

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专利权人:

ABLEXIS; LLC

发明人:

SHIZUYA, HIROAKI,GREEN, LARRY

申请号：

DK09751700

公开号：

DK2288623T3

申请日:

2009.05.22

申请国别(地区):

DK

年份:

2014

代理人:

摘要：

The present invention describes a single variable domain comprising a human VL domain segment, a DH domain segment, and a human JL domain segment. Provided is also a polynucleotide encoding a respective single variable domain. Further provided are a non-human mammalian cell with a genome that encodes the single variable domain and a hybridoma cell derived from such a non-human mammal.

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中国工程科技知识中心

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http://www.ckcest.cn/home/