A system and method for controlling a medical imaging device is provided. The system includes a medical imaging device. The system further includes a medical instrument. Further, the system includes a navigation subsystem that is configured to track the medical instrument. Furthermore, the system includes a control subsystem that communicates with the navigation subsystem. The control subsystem is configured to correlate at least one of orientation, position and motion of the medical instrument with a function of the medical imaging device. The control subsystem is further configured to direct the medical imaging device to perform the function associated with the medical imaging device, based on the correlation.