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ショウガオールとカプリン酸を含む抗カンジダ活性組成物
专利权人:
TEIKYO UNIV
发明人:
INOUE SHIGEHARU,井上 重治,TAKAHASHI MIKI,高橋 美貴,ABE SHIGERU,安部 茂
申请号:
JP2012087908
公开号:
JP2013194051A
申请日:
2012.03.21
申请国别(地区):
JP
年份:
2013
代理人:
摘要:
PROBLEM TO BE SOLVED: To provide a new composition with an anticandidal activity which achieves a more powerful effect on candidiasis of a skin and a mucous membrane, including elderly persons mycotic stomatitis and females vaginal candidiasis, both of which particularly are infectious diseases with a lot of numbers of patients and tend to have a relapse, than conventional products, which can be used for a long period of time without worrying about a risk of any side effect and/or of any resistant bacteria, and which is easily obtainable and usable for a patient.SOLUTION: Although both of shogaol which is an ingredient of a flavor plant, and capric acid which is an ingredient of a dry crude drug and is also a food additive, independently exhibit an anticandidal activity, a synergism is exerted when both are used together, and as a result their effect can be improved remarkably. Moreover, it is easy for both shogaol and capric acid to obtain high purity products, and both are approved of using for food. Therefore, both shogaol and capric acid can be applied to a wide range of products, ranging from medicine to food, and when they are put to a practical use, a patient can easily obtain and use a certain product. Although mycotic stomatitis and vaginal candidiasis tend to have a relapse, when the composition includes a plant constituent or a food additive, a risk caused by an application of an antifungal agent is not to be worried about, and the patient can use the composition at ease. Moreover, when compared at an equivalent level of effectiveness, the product, making full use of the synergism, can significantly lower an added amount of each ingredient. In a food industry in which flavor is regarded as important, a flexibility of formulation increases, and expansion of application products is achieved.COPYRIGHT: (C)2013,JPO&INPIT【課題】皮膚や粘膜のカンジダ症、とくに高齢者の口腔カンジダ症や女性の膣カンジダ症は、いずれも患者数が多く、かつ再発しやすい感染症である。カンジダは常在性真菌であり、また抗真菌剤による治療は、副作用や耐性菌出現のリスクがあって長期間の使用は限定されるため、再発を抑えることは困難である
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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