PROBLEM TO BE SOLVED: To provide a novel compound which inhibits one or a plurality of protein in a Wnt pathway and is useful against diseases or disorders related to tumor growth, cell proliferation or angiogenesis and a pharmaceutical composition containing the compound.SOLUTION: There are provided a compound having an imidazo[4,5-c]pyridine-2-yl-1H-indazole skeleton, where a compound represented by the following formula is a representative example, and a pharmaceutical composition containing the compound.EFFECT: The pharmaceutical composition exhibits effects on cancer, diabetic retinopathy, neovascular glaucoma, rheumatic arthritis, psoriasis, fungus and viral infection, bone or cartilage diseases, Alzheimer disease, osteoarthritis, genetic diseases caused by mutation of a Wnt signal pathway component or the like.SELECTED DRAWING: None【課題】Ｗｎｔ経路における１つ又は複数のタンパク質を阻害し、腫瘍成長、細胞増殖、又は血管形成に関連する疾患又は障害に対して有用な新規化合物、及び該化合物を含有する薬学的組成物の提供。【解決手段】下式で表される化合物を代表例とする、イミダゾ［４，５－ｃ］ピリジン－２－イル－１Ｈ－インダゾール骨格を有する化合物、及び該化合物を含有する薬学的組成物。【効果】該薬学的組成物は、癌、糖尿病性網膜症。新生血管緑内障、関節リウマチ、乾癬、真菌又はウイルス感染、骨又は軟骨疾患、アルツハイマー病、骨関節症、Ｗｎｔシグナル伝達成分の突然変異によって引き起こされる遺伝疾患などに対して効果を示す。【選択図】なし
