您的位置: 首页 > 农业专利 > 详情页

INHIBITEUR D'URAT1
专利权人:
J-PHARMA CO., LTD.; LTD.;NIPPON CHEMIPHAR CO.;合資会社ディ・スリー研究所;NIPPON CHEMIPHAR CO., LTD.;日本ケミファ株式会社;DETHREE RES. LAB. INC.;ジェイファーマ株式会社
发明人:
ENDO, Tsuyoshi,遠藤 剛,KOBAYASHI, Kunio,小林邦夫,TANAKA, Hiroto,田中博人,SAITO, Daisuke,齊藤 大祐,HIRANO Masuharu,平野 益治,ENDOU, Hitoshi,遠藤 仁,ANZAI, Naohiko,安西 尚彦,遠藤 剛,齊藤 大祐,平野 益治,遠藤 仁,安西 尚彦
申请号:
JPJP2015/086482
公开号:
WO2016/108282A1
申请日:
2015.12.28
申请国别(地区):
JP
年份:
2016
代理人:
摘要:
A compound represented by general formula (III), and the use of a tautomer or stereoisomer of said compound, or a pharmacologically acceptable salt or solvate thereof, as a treatment for gout or hyperuricemia. (III) (In the formula, R1a, R2a, R6a and R7a represent hydrogen atoms, C1-8 alkyl groups, C1-8 alkoxy groups, or cyano groups or the like, R3a and R8a represent elements or groups that bond with the two carbon atoms that bond R3a and R8a to form benzene rings, or five-membered ring heteroaryl rings containing, as constituent elements, 1-3 hetero atoms selected from nitrogen atoms, oxygen atoms and sulfur atoms, R4a and R5a represent elements or groups that bond with the two carbon atoms that bond R4a and R5a to form benzene rings, or represent the same as the previously mentioned R1a, Wa represents CR10a or N, and here, R10a represents the same as the previously mentioned R1a, Xa represents an oxygen atom or a sulfur atom or the like, and Ya represents a C1-8 alkylene chain. The alkylene chain may be substituted with a C1-8 alkyl group or the like, the alkylene chain may be a straight-chain alkylene chain or a branched-chain alkylene chain, and the branched-chain alkylene chain may have a 3-7 member ring formed by a side chain that bonds to a same or different carbon atoms bonding with these bonded carbon atoms, and may have a double bond partway along. Za represents CO2H or the like.)L'invention met en oeuvre un composé représenté par la formule générale (III), un tautomère, un stéréoisomère ou un sel pharmaceutiquement acceptable de ce composé, ou encore l'utilisation d'un solvate de ceux-ci en tant que médicament contre la goutte ou l'hyperuricémie. Dans la formule générale (III): R1a, R2a, R6a et R7a représentent un atome d'hydrogène, un goupe alkyle de 1 à 8 atomes de carbone, un groupe alcoxy de 1 à 8 atomes de carbone, un groupe cyano ou similaire; R3a et R8a forment un cycle de benzène formé de R3a et R8a liés à deux atomes d'hydrogène, ou un cycle hét
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

意 见 箱

匿名:登录

个人用户登录

找回密码

第三方账号登录

忘记密码

个人用户注册

必须为有效邮箱
6~16位数字与字母组合
6~16位数字与字母组合
请输入正确的手机号码

信息补充