Godwin, Antony Robert,Pedone, Elisa,Choi, Ji-Won,Brocchini, Stephen James,Shaunak, Sunil
申请号：
ES09167191
公开号：
ES2632515T3
申请日:
2004.07.12
申请国别(地区):
ES
年份:
2017
代理人:
摘要：
A compound of the general formula ** ** Formula in which one of X and X represents a homo- or co-polymer selected from the group consisting of polyalkylene glycols, polyvinylpyrrolidones, polyacrylates, polymethacrylates, polyoxazolines, polyvinylalcohols, polyacrylamides, polymethacrylamides, copolymers HPMA, polyesters, polyacetals, poly (ortho esters), polycarbonates, poly (imidocarbonates), maleic or styrene-maleic anhydride, polysaccharides, or polyglutamic acids divinyl anhydride, any of said homo- or copolymers optionally derivatised or functionalised and the other represents a hydrogen atom each Q independently represents a linking group W represents a keto group CO, an ester group -O-CO-, or a sulfone group -SO2-, or a moiety preparable by reduction of such a group or, if X represents a polyethylene glycol, XQW- together may represent a cyano group each of Z1 and Z2 independently represents a protein, each of which is attached to A and B through an amino group or Z1 and Z2 together represent a single protein that is bound to A and B via two amino groups A is a C1-5 alkylene or alkenylene chain and B is a bond or C1-4 alkylene or alkenylene chain.Un compuesto de la fórmula general**Fórmula** en la que uno de X y X representa un homo o co-polímero seleccionado del grupo que consiste en polialquilenglicoles, polivinilpirrolidonas, poliacrilatos, polimetacrilatos, polioxazolinas, polivinilalcoholes, poliacrilamidas, polimetacrilamidas, copolímeros de HPMA, poliésteres, poliacetales, poli(ortoésteres), policarbonatos, poli(imidocarbonatos), copolímeros de diviniléter-anhídrido maleico o de estireno-anhídrido maleico, polisacáridos, o ácidos poliglutámicos, estando cualquiera de dichos homo- o copolímeros opcionalmente derivatizado o funcionalizado y el otro representa un átomo de hidrógeno cada Q representa independientemente un grupo enlazador W representa un grupo ceto CO, un grupo éster -O-CO-, o un grupo sulfona -SO2-, o un resto que se puede preparar median
