A cleaning device between teeth includes a holding part, a fixing part and a cleaning part.The gripping part has a gripping surface and a antiskid structure formed on the gripping surface. The antiskid structure has a plurality of mutually spaced convex parts and concave parts. The top end of the convex part is flush with the gripping surface, the concave part is lower than the gripping surface, and the gripping part has nano silver micro particles.The fixing part is on one side of the holding part, and the fixing part has nano silver particles.The cleaning part has a bristle on one side of the fixing part.Thus, the tooth dirt can be cleaned and the bactericidal effect can be achieved.一種齒間清潔裝置包括一握持部、一固定部、及一清潔部。所述握持部具有一握持面及一形成在所述握持面的防滑結構，所述防滑結構具有多個相互間隔的凸部及凹部，所述凸部的頂端與所述握持面切齊，該凹部低於握持面，且所述握持部具有奈米銀微粒。固定部位於握持部的一側，固定部具有奈米銀微粒。清潔部位於所述固定部的一側，清潔部具有一刷毛。藉此，可以清潔牙齒污垢且可達到殺菌效果。
