AULT, BRIAN,ORLEMANS, EVERARDUS,PLACHETKA, JOHN R.,SOSTEK, MARK
申请号：
CA2736547
公开号：
CA2736547C
申请日:
2009.09.03
申请国别(地区):
CA
年份:
2016
代理人:
摘要：
The present disclosure is directed to the use of naproxen, or pharmaceuticallyacceptable salt thereof, andesomeprazole, or pharmaceutically acceptable salt thereof in the manufactureof a pharmaceutical composition in unit dose form,wherein said esomeprazole, or pharmaceutically acceptable salt thereof, isreleased from said unit dose form at a specified pH,wherein one unit dose form is for administration as an AM dose and a secondunit dose form is for administration about 10 hourslater as a PM dose to target a specified pharmacokinetic profile.
