A compound of Formula (I), or a pharmaceutically acceptable salt thereof ** Formula ** where W, X, Y and Z of ring A form the group ** Formula ** or the group ** Formula ** where R4 is selected from the group consisting of: a) -hydrogen； b) -C1-6 alkyl； and c) -C (O) -C1-6 alkyl； R5 is -G3-L2-Q2-L3-G4, where L2 is selected from the group consisting of: -CH2-, -O-, -N (R26) -, and -C (O) -, where R26 it is selected from the group consisting of: hydrogen, -alkyl, -aryl, and -alkylene-aryl； L3 is a direct link； Q2 is a C1-C10 alkylene group； G3 is a phenylene group, wherein G3 is optionally substituted 1-4 times with substituents independently selected from R8, wherein R8 is selected from Rb； and G4 is selected from the group consisting of: cycloalkyl, phenyl, pyridinyl, benzothiofeneyl, benzothiazolyl, where G4 is optionally substituted 1-4 times with substituents independently selected from R9, wherein R9 is selected from Rb； R is - (CH2) p-G1-L1-G2, where p is 1； L1 is a direct link； G1 is phenyl, wherein G1 is optionally substituted 1-4 times with substituents independently selected from R10, where R10 is Rb； G2 is selected from the group consisting of: indole, pyridine, pyrimidine, quinoline, and isoxazole, wherein G2 is optionally substituted 1-4 times with substituents independently selected from R11, where R "is Rb, R1 is selected from the group that consists of: -CO2H and -CO2R12, where R12 is selected from the group consisting of: -C1-10 alkyl, -cycloalkyl； and -aryl, where R12 is optionally substituted 1-4 times with a group independently selected from Rc ； R2 is selected from the group consisting of: -hydrogen and -C1-10 alkyl； R3 is either selected from the group consisting of: a) -C1-10 alkyl, b) -phenyl, c) -thiopheneyl, d) - furanyl, e) -pyridyl, f) -C1-10 alkylene-pyridyl, g) -C1-10 alkylene-aminothiazolyl, h) -C1-10 alkylene-imidazolyl, i) -C1-10 alkylene-oxazolyl, j) - C1-10 alkylene thiopheneyl, k) -C2-10 alkynylene phenyl, I) -C2-10 alkynylene thio
