The invention relates to a device for mixing a polymethyl methacrylate bonecementformed of two starting components (1, 2) and for storing the startingcomponents (1, 2)of the bone cement, said device having a tubular cartridge (3, 4) with acylindricalinterior, wherein a powder (1) is contained as first starting component in afront part ofthe interior of the cartridge (3, 4) and a container (9) containing a monomerliquid (2) assecond starting component is arranged in a rear part of the interior of thecartridge (3,4), wherein a discharge piston (6) is arranged between the container (9) andthe powder(1), and wherein a conveying piston (5) is arranged on the side of thecontainer (9)opposite the discharge piston (6), wherein the discharge piston (6) and theconveyingpiston (5) are arranged in the interior of the cartridge (3, 4) movably in thelongitudinaldirection, wherein a conduit means (22) is provided, which connects the frontpart andthe rear part of the interior of the cartridge (3, 4) to one another in amanner permeablefor the monomer liquid (2) and for gases and which is impermeable for thepowder (1).The invention also relates to methods for mixing the starting components (1,2) and to amethod for producing a prepacked PMMA cement cartridge system suitable formixingand applying a PMMA bone cement dough (44).