Compounds type 1- (substituted benzyl) -5-trifluoromethyl-2- (1H) pyridone, which have the structural formula (XIII), ** Formula ** where R1-R4, R12 are selected from H, NO2, hydroxyl, amino , halogen atom, C1-C6 alkoxy, NR10R11, OR13, C (O) R14, OC (O) R14, C1-C6 alkyl, C1-C6 haloalkyl, C2-C6 alkenyl； where R1 ~ R4, R12 are not simultaneously H, R14 is selected from C1-C6 alkyl, R13 is selected from hydroxyalkyl or alkoxyalkyl； where in NR10R11, R10 and R11 are selected from H, C1-C6 hydroxyalkyl, esterified C1-C6 hydroxyalkyl, C1-C6 alkoxyalkyl or structural formula XIV and R10 and R11 are not simultaneously H； ** Formula ** where R5 is selected between H, C1-C6 alkyl, C1-C6 haloalkyl, C1-C6 hydroxyalkyl and C2-C6 alkenyl； R6-R9 are selected from H, C1-C6 alkoxy,>； = O, C1-C4 alkyl, C1-C4 haloalkyl, C1-C4 hydroxyalkyl and C2-C4 alkenyl； X is selected from N and CH； Y is selected from N, O and CH； and when Y is O, then R5 is absent and n is 1-6； and pharmaceutically acceptable salts thereof.Compuestos tipo 1-(bencilo sustituido)-5-trifluorometil-2-(1H)piridona, que tienen la fórmula estructural (XIII),**Fórmula** donde R1-R4, R12 se seleccionan entre H, NO2, hidroxilo, amino, átomo de halógeno, alcoxilo C1-C6, NR10R11, OR13, C(O)R14, O-C(O)R14, alquilo C1-C6, haloalquilo C1-C6, alquenilo C2-C6； donde R1~R4, R12 no son simultáneamente H, R14 se selecciona entre alquilo C1-C6, R13 se selecciona entre hidroxialquilo o alcoxialquilo； donde en NR10R11, R10 y R11 se seleccionan entre H, hidroxialquilo C1-C6, hidroxialquilo C1-C6 esterificado, alcoxialquilo C1-C6 o la fórmula estructural XIV y R10 y R11 no son simultáneamente H；**Fórmula** donde R5 se selecciona entre H, alquilo C1-C6, haloalquilo C1-C6, hidroxialquilo C1-C6 y alquenilo C2-C6； R6-R9 se seleccionan entre H, alcoxilo C1-C6, >；=O, alquilo C1-C4, haloalquilo C1-C4, hidroxialquilo C1-C4 y alquenilo C2-C4； X se selecciona entre N y CH； Y se selecciona entre N, O y CH； y cuando Y es O, entonces R5 está ausen
