A nuclear medicine (NM) multi-head imaging system is provided that includes a gantry, plural detector units, and at least one processor. The gantry defines a bore configured to accept an object to be imaged. The plural detector units are mounted to the gantry. Each detector unit defines a corresponding view oriented toward a center of the bore, and is configured to acquire imaging information over a sweep range. The at least one processor is configured to dynamically determine at least one boundary of an acquisition range corresponding to an uptake value of the object to be imaged for at least one of the detector units. The acquisition range is smaller than sweep range. The at least one processor is also configured to control the at least one detector unit to acquire imaging information over the acquisition range.