SAWHNEY, AMARPREET S.,JARRETT, PETER,BASSETT, MICHAEL,BLIZZARD, CHARLES D.
申请号：
CA2750242
公开号：
CA2750242C
申请日:
2010.02.12
申请国别(地区):
CA
年份:
2018
代理人:
摘要：
An embodiment is a medicalprosthesis for blocking or reducing tear flowthrough a punctum or canaliculus of a humaneye and delivering a drug to the eye that comprisesa dehydrated covalently crosslinkedsynthetic hydrophilic polymer hydrogel withdimensions to pass through a punctalacrimali, with the dehydrated hydrogel absorbingphysiological water to swell to at least1 mm in cross-sectional width and conformablyfit a canaliculus, with the hydrogelcomprising a therapeutic agent dispersedthrough the hydrogel for release to an eye,with the hydrogel having a water content of atleast about 50% by weight or volume whenallowed to fully hydrate in vitro in physiologicalsaline.
