AMARPREET S SA WHNEY,PETER JARRETT,MICHAEL BASSETT,CHARLES D BLIZZARD
申请号:
IN6272/DELNP/2011
公开号:
IN2011DN06272A
申请日:
2011.08.18
申请国别(地区):
IN
年份:
2012
代理人:
摘要:
An embodiment is a medical prosthesis for blocking or reducing tear flow through a punctum or canaliculus of a human eye and delivering a drug to the eye that comprises a dehydrated covalently crosslinked synthetic hydrophilic polymer hydrogel with dimensions to pass through a puncta lacrimali, with the dehydrated hydrogel absorbing physiological water to swell to at least 1 mm in cross-sectional width and conformably fit a canaliculus, with the hydrogel comprising a therapeutic agent dispersed through the hydrogel for release to an eye, with the hydrogel having a water content of at least about 50% by weight or volume when allowed to fully hydrate in vitro in physiological saline.