Peter Jarrett,Michael Bassett,Charles D. Blizzard,Amarpreet S. Sawhney
申请号：
US13777103
公开号：
US20130172268A1
申请日:
2013.02.26
申请国别(地区):
US
年份:
2013
代理人:
摘要：
An embodiment is a medical prosthesis for blocking or reducing tear flow through a punctum or canaliculus of a human eye and delivering a drug to the eye that comprises a dehydrated covalently crosslinked synthetic hydrophilic polymer hydrogel with dimensions to pass through a puncta lacrimali, with the dehydrated hydrogel absorbing physiological water to swell to at least 1 mm in cross-sectional width and conformably fit a canaliculus, with the hydrogel comprising a therapeutic agent dispersed through the hydrogel for release to an eye, with the hydrogel having a water content of at least about 50% by weight or volume when allowed to fully hydrate in vitro in physiological saline.
