The substance refers to the crystalline smoke salt extracted from (s) - [3,4-fluoro-2 - (2-fluoro-4-iodoaniline) phenyl, [3-hydroxy-3 - (piperidin-2-il) azeidin-1-il) methanol; in addition, it also refers to its pharmacological components, including its salts. It also refers to the use of this salt as a treatment for melanoma, rectal cancer, lung cancer and other cancers.Esta referido a la sal de fumarato cristalina de (S)-[3,4-difluoro-2-(2-fluoro-4-yodofenilamino)fenil] [3-hidroxi-3-(piperidin-2-il)azetidin-1-il]-metanona; ademas, a sus composiciones farmaceuticas que comprende la sal del mismo. Tambien se refiere al uso de esta sal en metodos para tratar canceres como melanoma, cancer colorrectal, cancer de pulmon, entre otras