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Crystalline fumarate Salt of (S) - 3,4 - difluoro - [2 - (4 - fluoro - yodofenilamino) phenyl] [3 - hydroxy - 3 - (2 - azetidin piperidin yl) - triazin-1-yl] - methanone
专利权人:
EXELIXIS INC.
发明人:
BROWN, Adrian St. Clair
申请号:
CO2018000086
公开号:
CO2018000086A2
申请日:
2018.01.05
申请国别(地区):
CO
年份:
2018
代理人:
摘要:
Abstract this description refers to the Crystalline fumarate Salt of (S) - 3,4 - difluoro - [2 - (4 - fluoro - yodofenilamino) phenyl] [3 - hydroxy - 3 - (2 - azetidin piperidin yl) - triazin-1-yl] - methanone.The description also relates to pharmaceutical compositions that include the Crystalline fumarate Salt of (S) - [32 - (4 - difluoro - 2-fluoro-4 - yodofenilamino) phenyl] [3 - hydroxy - 3 - (2 - azetidin piperidin yl) - triazin-1-yl] - methanone.The description also relates to methods for treating cancer comprising administering to a patient in need of Crystalline fumarate Salt of (S) - [32 - (4 - difluoro - 2-fluoro-4 - yodofenilamino) phenyl] [3 - hydroxy - 3 - (2 - azetidin piperidin yl) - triazin-1-yl] - methanone.RESUMEN La presente descripción se refiere a la sal de fumarato cristalina de (S)-[3,4-difluoro-2-(2-fluoro-4-yodofenilamino)fenil][3-hidroxi-3-(piperidin-2-il)azetidin-1-il]-metanona. La descripción también se refiere a composiciones farmacéuticas que comprenden la sal de fumarato cristalina de (S)-[3,4-difluoro-2-(2-fluoro-4-yodofenilamino)fenil][3-hidroxi-3-(piperidin-2-il)azetidin-1-il]-metanona. La descripción también se refiere a métodos para tratar cánceres que comprenden administrarle a un paciente que lo necesita la sal de fumarato cristalina de (S)-[3,4-difluoro-2-(2-fluoro-4-yodofenilamino)fenil][3-hidroxi-3-(piperidin-2-il)azetidin-1-il]-metanona.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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