An enteral feeding device and methods of using such device to unclog a feeding tube are described herein, wherein the device includes a first tube having a distal end and a proximal end. The first tube defines a feeding lumen that extends longitudinally through at least a portion of the first tube. The first tube has at least one distal opening capable of allowing introduction of nutrients and/or medicaments from within the feeding lumen through the opening into a gastrointestinal area of a patient when the enteral feeding tube is implanted in a patient. The device also has a wall having a distal end and a proximal end, which extends longitudinally within at least a portion of the first tube. The wall has an exterior surface and an interior surface. At least a portion of the exterior surface of the wall contacts the feeding lumen. The interior surface of the wall and/or the first tube define an inflatable lumen having a proximal end and a distal end, wherein the inflatable lumen extends longitudinally through at least a portion of the feeding lumen, and wherein the wall is capable of changing a volume of the feeding lumen by allowing for deflation of the inflatable lumen through removal of a fluid from the inflatable lumen and/or inflation of the inflatable lumen through introduction of a fluid into the inflatable lumen.