Peter W. Glunz,Doree F. Sitkoff,Mandar Shrikrishna Bodas,Navnath Dnyanoba Yadav,Sharanabasappa Patil,Prasanna Savanor Maddu Rao
申请号:
US15554741
公开号:
US10112929B2
申请日:
2016.03.08
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The present invention provides compounds of Formula (I): or stereoisomers, tautomers, or pharmaceutically acceptable salts thereof, wherein all the variables are as defined herein. These compounds are selective ROCK inhibitors. This invention also relates to pharmaceutical compositions comprising these compounds and methods of treating cardiovascular, smooth muscle, oncologic, neuropathologic, autoimmune, fibrotic, and/or inflammatory disorders using the same.