NTI-ADDAE, KWAME W.,WALDO, MICHAEL,O'NEIL, SIMON ADAM,VAN ALSTEN, JOHN GREGG,MACIKENAS, DAINIUS,MUDUNURI, PRAVEEN,SHI, YI,LEDEBOER, MARK WILLEM,JURKAUSKAS, VALDAS,MEDEK, ALES,JONES, STEVEN,BYRN, RANDA
申请号：
PL14802787
公开号：
PL3068776T3
申请日:
2014.11.12
申请国别(地区):
PL
年份:
2019
代理人:
摘要：
Polymorphic forms of Compound (1) or a pharmaceutically acceptable salt thereof, wherein Compound (1) is represented by the following structural formula:are Form A of HCl salt of Compound(1)·1/2H<；sub>；2<；/sub>；O, Form F of HCl salt of Compound(1)·3H<；sub>；2<；/sub>；O, Form D of HCl salt of Compound(1),Form A of Compound(1),and Form A of tosylate salt of Compound(1).Such polymorphic forms are employed for treating influenza, inhibiting the replication of influenza viruses, or reducing the amount of influenza viruses in a biological sample or in a subject.
