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TRANSGENIC NON-HUMAN ANIMAL AND USES THEREOF
专利权人:
SANOFI
发明人:
DRESSLER, HOLLY,ECONOMIDES, KYRIAKOS D.,PANG, ZHEN,POLITES, HARRY GREGORY
申请号:
SG2012042370
公开号:
SG181593A1
申请日:
2010.12.17
申请国别(地区):
SG
年份:
2012
代理人:
摘要:
The present invention relates generally to transgene constructs, transgenic non-human animals comprising transgene constructs, methods of making and methods of using the transgenic non-human animals comprising transgene constructs. An embodiment of the invention relates to methods of assaying the activation of GPCR ligands non-invasively in whole animals, tissue slices, or in native cells using a transgenic model containing a bioluminescent transgene reporter system that is responsive to pathway modulation following ligand binding of GPCR receptors.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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