Leslie R. Berry,Vera Ignjatovic,Paul T. Monagle,Anthony K. Chan
申请号:
US13398379
公开号:
US09091700B2
申请日:
2012.02.16
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The invention provides novel reagents and methodologies for detecting free versus bound enzyme. It is particularly useful to detect thrombin when it is not bound to A2M in the presence of thrombin bound to A2M by using a modified substrate that is sterically hindered from reacting with the bound thrombin.