Han Li,Dorothea Kominos,Jie Zhang,Alla Pritzker,Matthew Davison,Nicolas Baurin,Govindan Subramanian,Xin Chen
申请号：
US14382798
公开号：
US20150050270A1
申请日:
2013.03.15
申请国别(地区):
US
年份:
2015
代理人:
摘要：
The invention provides antibodies that specifically bind to Kallidin or des-Arg10-Kallidin. The invention also provides pharmaceutical compositions, as well as nucleic acids encoding anti-Kallidin or des-Arg10-Kallidin antibodies, recombinant expression vectors and host cells for making such antibodies, or fragments thereof. Methods of using antibodies of the invention to modulate Kallidin or des-Arg10-Kallidin activity or detect Kallidin or des-Arg10-Kallidin or, either in vitro or in vivo, are also provided by the invention. The invention further provides methods of making antibodies that specifically bind to des-Arg9-Bradykinin and des-Arg10-Kallidin-like peptide.
