KOMINOS, DOROTHEA,ZHANG, JIE,PRITSKER, ALLA,DAVISON, MATTHEW,BAURIN, NICOLAS,SUBRAMANIAN, GOVINDAN,CHEN, XIN,LI, HAN
申请号：
PH12014501970
公开号：
PH12014501970A1
申请日:
2014.09.03
申请国别(地区):
PH
年份:
2014
代理人:
摘要：
The disclosure provides antibodies that specifically bind to Kallidin or des-Arg10-Kallidin. The disclosure also provides pharmaceutical compositions, as well as nucleic acids encoding anti-Kallidin or des- Arg10-Kallidin antibodies, recombinant expression vectors and host cells for making such antibodies, or fragments thereof. Methods of using antibodies of the disclosure to modulate Kallidin or des-Arg10- Kallidin activity or detect Kallidin or des-Arg10-Kallidin or, either in vitro or in vivo, are also provided by the disclosure. The disclosure further provides methods of making antibodies that specifically bind to des-Argg- Bradykinin and des-Arg10-Kallidin-like peptide.
