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ANTIBODIES TO BRADYKININ B1 RECEPTOR LIGANDS
专利权人:
SANOFI
发明人:
KOMINOS DOROTHEA,ZHANG JIE,PRITSKER ALLA,DAVISON MATTHEW,BAURIN NICOLAS,SUBRAMANIAN GOVINDAN,CHEN XIN
申请号:
TN2014000395
公开号:
TN2014000395A1
申请日:
2014.09.19
申请国别(地区):
TN
年份:
2015
代理人:
摘要:
The disclosure provides antibodies that specifically bind to Kallidin or des-Arg10-Kallidin. The disclosure also provides pharmaceutical compositions, as well as nucleic acids encoding anti-Kallidin or des- Arg10-Kallidin antibodies, recombinant expression vectors and host cells for making such antibodies, or fragments thereof. Methods of using antibodies of the disclosure to modulate Kallidin or des-Arg10- Kallidin activity or detect Kallidin or des-Arg10-Kallidin or, either in vitro or in vivo, are also provided by the disclosure. The disclosure further provides methods of making antibodies that specifically bind to des-Argg- Bradykinin and des-Arg10-Kallidin-like peptide.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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