PROBLEM TO BE SOLVED: To provide tablets prepared by a direct tableting method and containing a probiotic agent, a digestive enzyme agent, or both of them.SOLUTION: The tablets using crystalline cellulose-light anhydrous silicic acid conjugate as an excipient are obtained by mixing a powder, which is prepared by compounding the probiotic agent, the digestive enzyme agent, or both of them at the same time, and by directly tableting the powder.【課題】直接打錠法により製造した生菌剤や消化酵素剤及びその両方を含有する錠剤の提供。【解決手段】賦形剤として結晶セルロース・軽質無水ケイ酸結合体を用い、かつ生菌剤や消化酵素剤あるいは生菌剤と消化酵素剤を同時に配合した粉末を混合した後に直接打錠することを特徴とする。【選択図】なし