MEDIATEURS DE VOIES DE SIGNALISATION HEDGEHOG, COMPOSITIONS ET UTILISATIONS LIEES A CEUX-CI

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专利权人:

CURIS, INC.;GENENTECH, INC.

发明人:

申请号：

EP05818207.2

公开号：

EP1807074B1

申请日:

2005.11.03

申请国别(地区):

EP

年份:

2013

代理人:

摘要：

The present invention makes available methods and reagents for inhibiting aberrant growth states resulting from hedgehog gain-of-function, ptc loss-of-function or smoothened gain-of-function comprising contacting the cell with a hedgehog antagonist of formula (1), in a sufficient amount to aberrant growth state, e.g., to agonize a normal ptc pathway or antagonize smoothened or hedgehog activity.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/