Process for obtaining fluoride doped citrate coated amorphous calcium phosphate nanoparticles. This material has applications in biomedicine due to its biodegradability and bioactivity it also promotes cell adhesion and osteogeneration. In dentistry it may be used in toothpastes mouthwashes chewing gums gels and fluoride varnishes as a remineralising agent of dentine and enamel. It is based on two solutions formed by calcium chloride and sodium citrate on the one hand and by sodium monohydrogenophosphate and sodium carbonate with a fluoride compound on the other which are mixed at room temperature. The process is eco efficient and eco friendly as it does not leave any acid residue it consists of a single stage and it is the first time that an amorphous calcium phosphate coated with citrate and doped with fluoride which enhances its remineralising action is obtained.
