PALUCKA, ANNA KAROLINA,BANCHEREAU, JACQUES F.,UENO, HIDEKI
申请号:
CA2843200
公开号:
CA2843200A1
申请日:
2012.07.27
申请国别(地区):
CA
年份:
2013
代理人:
摘要:
Compositions and methods for eliciting therapeutic immunity and improving clinical outcomes in patients with pancreatic cancer are disclosed herein. The present invention describes a dendritic cell (DC)-vaccine comprising DCs pulsed with peptides derived from pancreatic cancer antigens for the therapy against pancreatic cancer. The vaccine described herein is safe, and leads to expansion of cancer specific T cells in patients with pancreatic cancer.