Hideki Ueno;Jacques F. Banchereau;Anna Karolina Palucka
发明人:
Anna Karolina Palucka,Jacques F. Banchereau,Hideki Ueno
申请号:
US13560534
公开号:
US20130028915A1
申请日:
2012.07.27
申请国别(地区):
US
年份:
2013
代理人:
摘要:
Compositions and methods for eliciting therapeutic immunity and improving clinical outcomes in patients with pancreatic cancer are disclosed herein. The present invention describes a dendritic cell (DC)-vaccine comprising DCs pulsed with peptides derived from pancreatic cancer antigens for the therapy against pancreatic cancer. The vaccine described herein is safe, and leads to expansion of cancer specific T cells in patients with pancreatic cancer.