4- amino-3-arylamino -6- arylpyrazole [3,4-D] pyrimidine derivatives and preparation method thereof and its application as antiviral drugs农业专利-农业学术服务平台

专利权人:: 第三專利投資有限兩合公司;第三专利投资有限两合公司;Dritte Patentportfolio Beteiligungsgesellschaft mbH & Co. KG

发明人:: MAKAROV, Vadim,V．马卡罗夫,V．馬卡羅夫,WUTZLER, Peter,P．武茨勒,SCHMIDTKE, Michaela,M．施米特克,DAHSE, HansMartin,HM．达赫塞,HM．達赫塞,V.马卡罗夫,V.馬卡羅夫,P.武茨勒,M.施米特克,HM.达赫塞,HM.達赫塞

摘要：: The present invention relates to 4- amino 3- arylamino -6- arylpyrazole [3,4-d] pyrimidine derivatives and preparation method thereof and as the application of antiviral drugs. The purpose of the present invention provides new compound as example with the drug of what treatment picornavirus infection in what, and the problem of can avoid known drug, especially drug resistance and the problem of not tolerating etc. Use the compound indicated with general formula I that can solve this task.本發明涉及4-氨基3-芳基氨基-6-芳基吡唑[3，4-d]嘧啶衍生物及其製備方法以及作爲抗病毒藥物的應用。本發明的目的在於提供新型化合物作爲例如用於治療細小核糖核酸病毒感染的藥物，且可避免已知藥物的問題，尤其是抗藥性和不耐受之類的問題。採用以通式I表示的化合物可解決這一任務。