PREPARATION IMMUNOTHÉRAPEUTIQUE DE BÊTA-GLUCANE

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专利权人:

Biothera; Inc.

发明人:

申请号：

EP13784589.7

公开号：

EP2844262B1

申请日:

2013.03.14

申请国别(地区):

EP

年份:

2018

代理人:

摘要：

This disclosure describes, in one aspect, a composition that includes a ²-glucan component and an antibody component that specifically binds to the ²-glucan. In another aspect, this disclosure describes a method of increasing a subject's response to ²-glucan immunotherapy. Generally, the method includes identifying the subject as a low binder of ²-glucan and administering to the subject a composition that comprises a ²-glucan moiety conjugated to the therapeutic antibody. In some cases, the therapeutic antibody can be an anti-tumor antibody.

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