GROSSMAN, WILLIAM J.,ANTONYSAMY, MARY A.,WALSH, RICHARD M.,NELSON, MARIANA I.,BOSE, NANDITA,DANIELSON, MICHAEL E.,MICHEL, KYLE S.
申请号：
CA2872010
公开号：
CA2872010A1
申请日:
2013.03.14
申请国别(地区):
CA
年份:
2013
代理人:
摘要：
This disclosure describes, in one aspect, a composition that includes a ß-glucan component and an antibody component that specifically binds to the ß-glucan. In another aspect, this disclosure describes a method of increasing a subject's response to ß-glucan immunotherapy. Generally, the method includes identifying the subject as a low binder of ß-glucan and administering to the subject a composition that comprises a ß-glucan moiety conjugated to the therapeutic antibody. In some cases, the therapeutic antibody can be an anti-tumor antibody.
