Grossman, William J.,Antonysamy, Mary A.,Walsh, Richard M.,Nelson, Mariana I.,Bose, Nandita,Danielson, Michael E.,Michel, Kyle S.
申请号：
AU2018200706
公开号：
AU2018200706A1
申请日:
2018.01.30
申请国别(地区):
AU
年份:
2018
代理人:
摘要：
#$%^&*AU2018200706A120180222.pdf#####ABSTRACT This disclosure describes, in one aspect, a method for identifying p-glucan binding to immune cells of a subject. Generally, the method includes obtaining a blood sample from the subject, the blood sample comprising immune cells, adding soluble f3-glucan to at least a portion of the blood sample and incubating the mixture under conditions allowing the soluble p-glucan to bind to the immune cells, and detecting soluble 3-glucan bound to the immune cells. In another aspect, this disclosure describes a method that generally includes identifying the subject as a low binder of P-glucan, and co-administering to the subject a soluble pglucan and an antibody preparation capable of converting the subject from a low binder to a high binder.
