A kind of preparation of nickel misfit object what releive inflammation drug purposes, which includes structure formula (I) and structure formula (II) at least one of them,, wherein L is solvent molecule. There is reactivity similar with the activated centre of nickel superoxide dismutase (NiSOD) is contained by the what nickel misfit object, oxidation activity object can be removed, therefore available what prepares the purposes of the drug for inflammation of releiving.一種鎳錯合物用於製備舒緩發炎之藥物的用途，該鎳錯合物包含結構式（I）與結構式（II）其中至少一者，，其中，Ｌ為溶劑分子。由於該鎳錯合物具有與含鎳超氧化物歧化酶(NiSOD)之活性中心相似的反應活性，可清除氧化活性物，因此可用於製備舒緩發炎之藥物的用途。
