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GLYCOENGINEERED ANTIBODY, ANTIBODY-CONJUGATE AND METHODS FOR THEIR PREPARATION
专利权人:
发明人:
申请号:
EP14790777.8
公开号:
EP2935611A1
申请日:
2014.10.14
申请国别(地区):
EP
年份:
2015
代理人:
摘要:
The invention relates to glycoengineered antibodies and antibody-conjugates. In particular, the invention relates to an antibody conjugate, prepared from an IgG antibody comprising one N-linked glycosylation site on the combination of a single heavy chain and single light chain, wherein the N-linked glycosylation site is a mutant N-linked glycosylation site as compared to its wild type counterpart. The invention further relates to methods for the preparation of the antibody-conjugates according to the invention.
来源网站:
中国工程科技知识中心
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http://www.ckcest.cn/home/

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