Floris Louis VAN DELFT,Remon VAN GEEL,Maria Antonia WIJDEVEN
申请号：
US15029198
公开号：
US20160257764A1
申请日:
2014.10.14
申请国别(地区):
US
年份:
2016
代理人:
摘要：
The invention relates to glycoengineered antibodies and antibody-conjugates. In particular, the invention relates to an antibody conjugate, prepared from an IgG antibody comprising one N-linked glycosylation site on the combination of a single heavy chain and single light chain, wherein the N-linked glycosylation site is a mutant N-linked glycosylation site as compared to its wild type counterpart. The invention further relates to methods for the preparation of the antibody-conjugates according to the invention.
