BOCK, MARK G.,WATT, ALAN PAUL,PORTER, RODERICK ALAN,HARRISON, DAVID,BOUTARD, NICOLAS FELIX PIERRE,LEVENETS, OLEKSANDR,FABRITIUS, CHARLES-HENRY ROBERT YVES,TOPOLNICKI, GRZEGORZ WITOLD
申请号：
CA3070515
公开号：
CA3070515A1
申请日:
2018.07.31
申请国别(地区):
CA
年份:
2019
代理人:
摘要：
The present disclosure relates to compounds of Formula (I): (I)； and to theirpharmaceutically acceptable salts, pharmaceutical compositions, methods ofuse, and methodsfor their preparation. The compounds disclosed herein are useful forinhibiting the maturationof cytokines of the IL-1 family by inhibiting inflammasomes and may be used inthe treatmentof disorders in which inflammasome activity is implicated, such asautoinflammatory and autoimmunediseases and cancers.
