Harrison, David,Watt, Alan Paul,Boutard, Nicolas,Fabritius, Charles-Henry,Galezowski, Michal,Kowalczyk, Piotr,Levenets, Oleksandr,Woyciechowski, Jakub
申请号:
AU2018234278
公开号:
AU2018234278A1
申请日:
2018.03.12
申请国别(地区):
AU
年份:
2019
代理人:
摘要:
The present disclosure relates to compounds of Formula (I): and to their pharmaceutically acceptable salts, pharmaceutical compositions, methods of use, and methods for their preparation. The compounds disclosed herein inhibit the maturation of cytokines of the IL-1 family by inhibiting inflammasomes and may be used in the treatment of disorders in which inflammasome activity is implicated, such as inter alia autoinflammatory and autoimmune diseases and cancers.