BOCK, Mark G.,WATT, Alan Paul,PORTER, Roderick Alan,HARRISON, David,BOUTARD, Nicolas Felix Pierre,LEVENETS, Oleksandr,FABRITIUS, Charles-Henry Robert Yves,TOPOLNICKI, Grzegorz Witold
申请号：
AU2018311198
公开号：
AU2018311198A1
申请日:
2018.07.31
申请国别(地区):
AU
年份:
2020
代理人:
摘要：
The present disclosure relates to compounds of Formula (I): (I)； and to their pharmaceutically acceptable salts, pharmaceutical compositions, methods of use, and methods for their preparation. The compounds disclosed herein are useful for inhibiting the maturation of cytokines of the IL-1 family by inhibiting inflammasomes and may be used in the treatment of disorders in which inflammasome activity is implicated, such as autoinflammatory and autoimmune diseases and cancers.
