HARRISON, DAVID,WATT, ALAN PAUL,BOUTARD, NICOLAS,FABRITIUS, CHARLES-HENRY,GALEZOWSKI, MICHAL,KOWALCZYK, PIOTR,LEVENETS, OLEKSANDR,WOYCIECHOWSKI, JAKUB
申请号：
CA3056302
公开号：
CA3056302A1
申请日:
2018.03.12
申请国别(地区):
CA
年份:
2018
代理人:
摘要：
The present disclosure relates to compounds of Formula (I): and to their pharmaceutically acceptable salts, pharmaceutical compositions, methods of use, and methods for their preparation. The compounds disclosed herein inhibit the maturation of cytokines of the IL-1 family by inhibiting inflammasomes and may be used in the treatment of disorders in which inflammasome activity is implicated, such as inter alia autoinflammatory and autoimmune diseases and cancers.
